Job Title:
Principal Clinical Scientist
Company: Alignerr
Location: New York City, NY
Created: 2026-04-15
Job Type: Full Time
Job Description:
Principal Clinical Scientist (AI Training)About the RoleWhat if your years of clinical trial expertise could directly shape how AI reasons about medical evidence, regulatory submissions, and patient outcomes? We're looking for a Principal Clinical Scientist to bring senior-level rigor to cutting-edge AI research - ensuring the clinical data and analyses powering next-generation AI systems meet the standards expected in real-world regulatory environments.This is a fully remote, flexible contract role built for experienced clinical scientists who want to work at the intersection of medicine and frontier technology. No AI background needed - just deep expertise in clinical research and regulatory science.Organization: AlignerrType: Hourly ContractLocation: RemoteCommitment: 10-40 hours/weekWhat You'll DoDesign and review clinical trial protocols used to generate high-quality, regulator-ready training datasets for AI systemsInterpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevanceEvaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory expectationsProvide expert, structured feedback that directly improves how AI models reason about clinical trial data, endpoints, and outcomesWork independently and asynchronously - fully on your own scheduleWho You AreSenior-level experience designing clinical trial protocols for regulatory submissionDeep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent regulatory bodiesStrong background in clinical research methodology, biostatistics, or translational scienceNaturally detail-oriented with a systematic, rigorous approach to scientific evaluationClear and precise written communicator comfortable providing structured, actionable feedbackNice to HavePrior experience with data annotation, data quality assurance, or evaluation systemsFamiliarity with AI tools or machine learning workflows in clinical or biomedical contextsBackground in pharmacovigilance, medical affairs, or health technology assessmentExperience working across multiple therapeutic areas or global regulatory jurisdictionsWhy Join UsWork directly on frontier AI systems making a real impact on clinical and biomedical researchFully remote and flexible - work when and where it suits youFreelance autonomy with the structure of meaningful, high-stakes scientific workInfluence how AI understands, evaluates, and communicates real-world clinical evidenceCollaborate with leading AI research teams and labs at the cutting edge of the fieldPotential for ongoing work and contract extension as new projects launch