Director, Portfolio Development Platform

CSL is transforming its R&D organization to accelerate innovation and create greater impact for patients. With a streamlined, project-led structure and a focus on collaboration, we're building a future-ready team that excels in dynamic biotech ecosystems. Joining CSL now means being part of an agile team committed to developing therapies that make a meaningful difference worldwide.Could you be our next Director, Portfolio Development Platform? The job is in our King of Prussia, PA or Maidenhead UK office. This is a hybrid position and is onsite three days a week. You will report to Senior Director, Portfolio Development Platform (TES).Job PurposeYou will be responsible for the strategic oversight, operational stability, and continuous advancement of critical biometrics and pharmacometrics technology platforms that enable clinical development execution and decision‑making.  This role ensures the reliable operation, scalability, and compliance of core systems supporting Biometrics and Pharmacometrics, including the Clinical Data Repository, Statistical Compute Environments, pharmacometric modeling and simulation platforms, and third‑party data ingestion capabilities.  The role requires an understanding of modeling and simulation, precision medicine, and advanced data analysis principles to effectively support pharmacometric and analytical systems.  Serving as the primary technical partner to the VP of Biometrics, the Director bridges biometrics and pharmacometrics strategy with technology execution, ensuring platforms are resilient, fit‑for‑purpose, and aligned with CSL’s development objectives.RESPONSIBILITIES AND ACCOUNTABILITIES1) Provide overall leadership and accountability for development platforms supporting Biometrics and Pharmacometrics.  Own the strategic roadmap for delivering systems and service capabilities across multiple business areas.2) Own the strategic IT relationship with senior business leaders, leveraging a deep understanding of the business strategies, priorities and challenges, to influence alignment of business objectives and its strategy for near and long term.  Serve as the primary technical and operational escalation point for the Biometrics and Pharmacometrics organizations, ensuring rapid issue resolution and minimal disruption to clinical, statistical, and modeling activities.3) Ensure platforms meet regulatory, data integrity, security, and inspection‑readiness requirements, including validated environments to support statistical analysis and pharmacometric modeling in regulated settings.4) Oversee vendor‑provided technologies and services support including performance management, roadmap alignment, and risk mitigation.5) Drive lifecycle management of development platforms, including upgrades, enhancements, cloud or high‑performance compute evolution, and reduction of technical debt.6) Establish and maintain platform governance, documentation standards, and operating processes to ensure long‑term sustainability, audit readiness, and reproducibility of analyses.7) Support development programs by ensuring analytical readiness, data accessibility, and robust computing environments across studies, programs, and therapeutic areas.8) Act as the main technology partner and advisor to the VP of Biometrics, translating biometrics and pharmacometrics strategy into scalable, secure, and compliant platform capabilities.9) Partner closely with Clinical Data Management, Statistical Programming, Pharmacometrics, Data Science, Regulatory, and IT stakeholders to enable seamless data flow and integrated analytical workflows.10) Champion automation and standardization to reduce manual data handling, accelerate analytical readiness, and improve workflow efficiency across development studies.QUALIFICATIONS:Bachelor’s degree in Computer Science, Information Systems, Engineering, Biostatistics, Pharmacometrics, Life Sciences, or a related discipline is required.  An advanced degree (Master’s or PhD) in a relevant technical or scientific field is preferred, particularly in areas related to biometrics, pharmacometrics, data science, or quantitative sciences. Minimum 10–15 years of experience supporting clinical development technology systems within the pharmaceutical, biotechnology, or life sciences industry. Demonstrated experience with clinical systems, statistical computing environments, data integration platforms, and technologies supporting clinical development. Working knowledge of pharmacometric concepts, modeling and simulation workflows, and the technical requirements needed to support these activities in regulated environments.  Strong experience operating within GxP settings, including system validation, inspection readiness, data integrity, and vendor‑managed solutions.  Ability to travel approximately 10–15%, including domestic and occasional international travel, to support global stakeholders, vendors, and program needs.About CSL BehringCSL Behring is a global biotherapeutics leader driven by our promise to save lives. Focused on serving patients’ needs by using the latest technologies, we discover, develop and deliver innovative therapies for people living with conditions in the immunology, hematology, cardiovascular and metabolic, respiratory, and transplant therapeutic areas. We use three strategic scientific platforms of plasma fractionation, recombinant protein technology, and cell and gene therapy to support continued innovation and continually refine ways in which products can address unmet medical needs and help patients lead full lives.CSL Behring operates one of the world’s largest plasma collection networks, CSL Plasma. Our parent company, CSL, headquartered in Melbourne, Australia, employs 32,000 people, and delivers its lifesaving therapies to people in more than 100 countries.To learn more about CSL, CSL Behring, CSL Seqirus and CSL Vifor  visit and CSL Plasma at BenefitsFor more information on CSL benefits visit How CSL Supports Your Well-being | CSL. You Belong at CSLAt CSL, Inclusion and Belonging is at the core of our mission and who we are. It fuels our innovation day in and day out. By celebrating our differences and creating a culture of curiosity and empathy, we are able to better understand and connect with our patients and donors, foster strong relationships with our stakeholders, and sustain a diverse workforce that will move our company and industry into the future. To learn more about inclusion and belonging visit Opportunity EmployerCSL is an Equal Opportunity Employer. If you are an individual with a disability and need a reasonable accommodation for any part of the application process, please visit

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