Postdoctoral Fellow

The Department of Investigative Medicine at Western Michigan University Homer Stryker M.D. School of Medicine invites applications for a Post-Doctoral Fellow research position in the laboratory of Thomas L. Rothstein MD, PhD, Chair of the Department of Investigative Medicine and Director of the Center for Immunobiology. Two kinds of projects are available. 1) Molecular Immunology-encompasses study of B1 cell development and function, including the role of human B1 cells and natural antibody in health and disease; BCR signaling pathways including receptor crosstalk and the IL-4-induced alternate pathway; B cell pathogenesis in lupus, rheumatoid arthritis, and other autoimmune dyscrasias; B cells and aging, including atherosclerosis and infectious diseases. 2) Cellular Proteostasis-encompasses study of stress- and mutation-related protein aggregation including novel assays for protein oligomers; mouse models of neurodegenerative diseases associated with dysfunctional protein aggregation; mechanism of aggregation prevention and aggregation resolution by the unique protein, FAIM. Postdoctoral fellows will lead research projects and have the opportunity to closely collaborate with experts in molecular biology, bioinformatics, genetics and biochemistry. The successful candidate is expected to carry out and publish cutting edge original research based on themes current in the Rothstein Lab, and to contribute to establishing and promoting a successful research environment. To share this posting, please use this link: 6096349:Career Search BENEFITS * Wellness reimbursement. * Continuing education and tuition reimbursement. * Employer-funded retirement plan. * Two medical plan options: PPO and High Deductible Health Plan (HDHP) with employer HSA contribution. * Flexible work solutions based on position and department. * Up to four weeks of PTO accrual beginning in year one. * Paid holidays. * Paid volunteer time. * Paid preferred holiday. DUTIES AND RESPONSIBILITIES * Direct involvement and participation in discovery-based research. * Conduct independent research and assist in the conduct of research. * Analyze data and interpret results to write reports and summaries of findings. * Maintain accurate records of tests conducted, results, data and patients tested. * Provides instruction in laboratory technique, instrumentation, and application of laboratory test procedures to new technologists or technicians and students. * Assists supervisor and lab members in the development of technical procedures and protocols. * Organizes and prioritizes work to meet specific goals and accomplishments. * Availability to work occasional overtime on weekends or evenings to complete time sensitive projects. * Acquires knowledge for new technology and policy/procedure revisions. * All other duties as assigned. Preference will be given to applicants with a recognized record of accomplishment, as evidenced by scholarly publications in the fields noted above. EDUCATION: * PhD in biochemistry, molecular biology, immunology, developmental biology, neuroscience, or a related field is required. Salary is competitive and commensurate with experience and accomplishments. A starting bonus may be provided and ability for one house hunting trip. About the Center for Immunobiology: The Rothstein Lab is located within the Center for Investigative Medicine, a new division within the Department of Investigative Medicine. The Center is endowed with the very latest instrumentation to speed research discovery. Common equipment includes 2 BD Influx and 1 Melody cell sorters, BD Fortessa and Thermo Fisher Attune flow cytometers, a Nikon confocal microscope, Illumina MySeq and Applied Biosystems SeqStudio (Sanger) sequencers a QuantStudio 3D digital PCR cycler, a QuantStudio 3 RealTime PCR cycler, a Bio-Rad FPLC system, a Bio-Rad gel doc system, a CTL multi-spectral ELISPOT reader, a BioTek visible/fluorescence/bioluminescence microplate reader, a BioTek microplate washer, 2 speedvacs, several bacterial incubator shakers, and ultra-, superspeed, and cytospin centrifuges, among other items. In addition to the Flow Cytometry and Imaging Core, the Equipment Core, and the Sequencing Core, three separate, fully equipped common rooms are outfitted for BL2, radioisotope, and tissue culture work. Additional separate rooms house core equipment, freezers, and an X-ray developer. The Center floor includes a cold room, a conference room, and a break room. The animal facility is located on the same floor and contains a PXi X-RAD 320 irradiator and a BL2 room for in vivo work with infectious agents. Support for the Center includes a flow cytometer/cell sorter/imaging core manager, an equipment specialist, and a business and operations manager. Also please send CV and the names of 3 references directly to Dr. Rothstein at and

Apply Now